Been using the Pisound HAT for close to a year. Originally bought one (took a while to get to me), played with it for a while. Ordered a second one after realizing that it was a pretty important tool for me. (Paid for the fast shipping, second time around.)
One Pisound-based setup is focused on MODEP (MOD Emulation for Pisound). Used it on several occasions, including during a Drone Day jam recently. The other is more of a music-focused Raspbian install, with Sonic Pi as a key piece of the puzzle but some Pd patches here and there.
The Pisound has quite a bit going for it. Not the least expensive, and some might argue that other platforms can give you similar results for cheaper but… Blokas has done a great job to integrate things, hardware and software. Those knobs are quite convenient. Even the single button on it is quite useful. The community is small but healthy. And there’s a whole lot to be said about MODEP, given how “plug and play” it is. There aren’t that many LV2 plugins available, but it’s more than enough to have quite a bit of fun without having to set things up every time.
The “normal” Raspbian setup allows you to boot directly into a given Pd patch or switch them around using a USB key. Haven’t really played with that but that’s a pretty neat feature.